Molecular Cloning and Characterization of Rat Genes Encoding Homologues of Human b-Defensins
نویسندگان
چکیده
HONG PENG JIA, JESSE N. MILLS, FARIBA BARAHMAND-POUR, DARRYL NISHIMURA, RAMA K. MALLAMPALI, GUOSHUN WANG, KERRY WILES, BRIAN F. TACK, CHARLES L. BEVINS, AND PAUL B. MCCRAY, JR.* Departments of Pediatrics, Internal Medicine, and Microbiology, University of Iowa College of Medicine, Iowa City, Iowa, and Department of Immunology, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio
منابع مشابه
Molecular cloning and characterization of rat genes encoding homologues of human beta-defensins.
beta-Defensins are cationic peptides with broad-spectrum antimicrobial activity that may play a role in mucosal defenses of several organs. They have been isolated in several species, and in humans, two beta-defensins have been identified. Here, we report the identification of two genes encoding beta-defensin homologues in the rat. Partial cDNAs were found by searching the expressed-sequence-ta...
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